To go to the Home Screen, move your mouse pointer to the top of the iPhone Mirroring window and click the Home Screen button in the upper right corner. Alternatively, click the bar at the bottom of the window or press Command-1 on your keyboard.

To open the App Switcher, move the pointer to the top of the iPhone Mirroring window and click the App Switcher button in the upper-right corner. Alternatively, press Command-2 on your keyboard.

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To go to the Spotlight search screen, use your mouse or trackpad to scroll up on the Home Screen. Alternatively, press Command-3 on your keyboard.